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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFHX4
All Species:
8.18
Human Site:
S2521
Identified Species:
20
UniProt:
Q86UP3
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UP3
NP_078997.3
3567
393730
S2521
M
P
P
Q
A
S
S
S
H
T
T
A
P
T
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001089817
3156
348587
P2174
K
Y
L
L
D
S
N
P
T
R
K
M
L
D
H
Dog
Lupus familis
XP_853266
3452
379865
A2403
M
P
P
Q
T
G
S
A
H
G
T
P
P
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJN2
3550
392304
A2503
M
P
P
Q
T
S
T
A
H
T
T
A
P
A
S
Rat
Rattus norvegicus
XP_226964
3593
395739
A2542
M
P
P
Q
A
S
T
A
H
T
T
A
P
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509863
3710
407348
T2619
Q
I
P
A
S
S
A
T
S
P
S
T
P
T
S
Chicken
Gallus gallus
O73590
3573
394529
S2509
M
P
P
Q
T
G
S
S
H
A
A
H
P
A
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684360
2686
299027
S1704
Y
D
K
Y
L
L
D
S
N
P
T
R
K
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393785
2962
326678
S1980
S
V
S
G
S
S
S
S
D
D
K
S
P
N
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798150
3296
366823
M2314
P
T
S
S
I
S
D
M
T
S
P
L
S
S
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.1
90.4
N.A.
90.8
91.8
N.A.
55.3
90.2
N.A.
52.6
N.A.
N.A.
21.1
N.A.
26
Protein Similarity:
100
N.A.
87.6
92.4
N.A.
94.1
94.9
N.A.
68.1
94
N.A.
61.7
N.A.
N.A.
36.2
N.A.
41.1
P-Site Identity:
100
N.A.
6.6
53.3
N.A.
66.6
73.3
N.A.
26.6
60
N.A.
13.3
N.A.
N.A.
26.6
N.A.
6.6
P-Site Similarity:
100
N.A.
13.3
60
N.A.
86.6
93.3
N.A.
60
60
N.A.
20
N.A.
N.A.
40
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
20
0
10
30
0
10
10
30
0
40
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
0
20
0
10
10
0
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
20
0
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
50
0
0
10
0
0
10
% H
% Ile:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
10
0
0
0
0
0
0
0
20
0
10
0
10
% K
% Leu:
0
0
10
10
10
10
0
0
0
0
0
10
10
0
10
% L
% Met:
50
0
0
0
0
0
0
10
0
0
0
10
0
10
0
% M
% Asn:
0
0
0
0
0
0
10
0
10
0
0
0
0
10
0
% N
% Pro:
10
50
60
0
0
0
0
10
0
20
10
10
70
0
20
% P
% Gln:
10
0
0
50
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% R
% Ser:
10
0
20
10
20
70
40
40
10
10
10
10
10
10
30
% S
% Thr:
0
10
0
0
30
0
20
10
20
30
50
10
0
20
20
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _